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What a Difference a Protocol Can Make February 2, 2006

I thought it might be interesting to do a side by side comparison of IVF #3 and IVF #4.

IVF #3     IVF #4
Long Lupron     Microdose Lupron
no break after previous FET cycle     forced break due to m/c
4 weeks on BCPs     10 days on BCPs
375IU of stims entire cycle     450IU dropping every two days down to 225IU
trigger on day 12     trigger on day 9
E2 1201 at trigger     E2 7542 at trigger
7 eggs retrieved     30 eggs retrieved
5 mature     22 mature
4 fertilized with ICSI     18 fertilized with ICSI
3 embryos on day 3, all 8 cells and above     18 embryos on day 3, 16- 8 cells and above
transferred 3 on day 3     transferred 3 on day 5
none to freeze     4 blasts frozen
result: pregnant but miscarried     result: ????


What a difference, huh? I mean, looking at that you would think that those were cycles from two different people. IVF #3 bordered on poor responder territory and IVF #4 was just the opposite. Crazy.

The truth of the matter is, though, that it doesn’t matter how things go along the way, it’s all about the end result. Will this cycle end up working? Who knows.

Quite honestly, I’m not in a pretty place right now. I’m in a “there’s no way it worked this time” place, and I can’t get out of it. I guess only time will tell if I’m right or not. It sure would be a shame to have such an awesome cycle only to have it wind up failing in the end.

Comments»

1. Becky K - February 2, 2006

That’s amazing! And I feel very positive for you, even if you don’t! And I am sending lots of peaceful and fruitful thoughts your way. (I’m praying for you too, but you don’t seem to like that… tough, I’m doing it anyway! ;-)) Thanks for sharing the journey with us.

2. One Half - February 2, 2006

oooo…I’m sorry you are having these kinds of thoughts…but I guess it is normal (to have the thoughts). Cuddle with the cat in the mean time. I am still cramping, that is crossing my fingers for you and am hoping that in fact all will go well and that you will take home a little baby in the end.

3. Leggy - February 2, 2006

Don’t forget the other big difference between this cycle and last- the MTHFR diagnosis and the drugs/vitamins that go with it. I’m hoping those make the difference between your last experience and a real live take home baby this time.

4. fisher queen - February 2, 2006

Just try to remember what a great starting off point you’ve had this time. You can’t know the outcome, but as of right now, things look good.

5. Portlairge - February 2, 2006

I know, the waiting fucks with your mind. Sending positive thoughts your way that beta day comes soon

6. Menita - February 2, 2006

Hang in there, hang in there, hang in there.
Thinking of you : )

7. Larisa - February 2, 2006

Very interesting to see the side-by-side comparison. Hoping it worked and will stick this time, despite your gut feelings.

8. Staci - February 2, 2006

That is just amazing….and, thanks also because I’m sure there are a lot of us who wanted to get their hands on the protocol you used for that last round :)

Like Leggy said, a big factor here is you know about the MTHFR issue and are treating for it.

After everything you’ve been through, I know it’s got to be so hard to actually picture a positive outcome but….try? At the risk of being annoying: You had an excellent cycle!! You have some great frosties waiting for you needed (and hopefully you’ll be using them for siblings). You are treating for an issue you didn’t know you had until this round. Rationally, you have every reason to think you have a very good chance here so try your best not to listen to those voices in your head telling you anything otherwise.

9. Avonlea - February 3, 2006

Aren’t your ICIS results out of the ordinary? 100% - that’s amazing.

I understand your feeling like you don’t want to believe this is it, I always felt that way and I’m not the veteran you are, stay there, better to be pleasantly surprised (and I think you will be).

10. thalia - February 3, 2006

It is, of course, completely natural to be feeling freaked out at this point. You’ve been through way too much to be able to stay on an even keel. I’m just delighted that you and the docs changed the protocol and had such amazing results. Now let’s hope those results continue through to the news in 10 days time or so.

Thinking of you.

11. Staci - February 3, 2006

I reread my post and think I came across wrong. I didn’t mean to say you should be pollyannaish about things (like that would ever happen anyway!). You know I’m not one who can maintain positive thinking myself when it comes to all this stuff. I think I lost that ability as early as failed attempt number 1! I just meant that, given the facts, it looks like you have as good a chance of this working as not so I don’t see the point in letting yourself become completely depressed over the next couple days by totally convincing yourself it didn’t work. Rather than positive thinking, how about just neutral thinking?!

12. Kath - February 3, 2006

Dear Amanda, ommmmmmm. ommmmmmm. ommmmmmmm. That’s me meditating for you, and wishing you the quickest week of your life, followed by the happiest news imaginable.

13. Kimmer - February 3, 2006

Amanda,

Hang in there chica, I’m thinking of you.
The 2ww is just soo damn hard.

14. lagringa - February 3, 2006

As always, I am thinking of you and crossing all body parts that will cross. Hang in there.

15. tazzy - February 3, 2006

I hope you get to have one more positive item to add at the end of that list for this ivf. it is amazing to see the differences in your two cycles. so far, so good!

16. kiwi - February 3, 2006

Crossing everything that can be crossed that this cycle will work!

17. elle - February 3, 2006

It’s totally understandable to feel defeatist - we all do it. But wowza, those #s look damn good! Hoping hard for you!

18. Shelley - February 3, 2006

Here’s to everything coming out right in the end. I’m thinking good thoughts for you.

Shelley

19. Jennie - February 3, 2006

is the tww over yet? it’s been ages, ok it hasnt really been ages but your not alone in the waiting so many of us are pulling for you and counting each day as a bonus. hang in there kiddo not long to go and those results are just incredible!

20. Pamplemousse - February 5, 2006

Hang in there, kiddo!